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This structural damage causes further mitochondrial failure and even more ROS leakage, creating a continuous "doom loop" of profound energy depletion, systemic inflammation, and the hallmark symptom of post-exertional malaise (PEM)

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adults diagnosed with obesity and roughly 35 million with Type 2 diabetes, its no wonder the popularity of GLP-1 therapies has skyrocketed, with numerous endorsements labeling them as miracle drugs. However, both doctors and patients are encountering challenges related to medication access, adherence, and insurance barriers

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