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In therapeutic dosage, paracetamol is largely metabolised by phase II processes (glucuronidation and sulphation) to stable metabolites, but between 5% and 10% also undergoes P450 metabolism to the toxic N -acetyl p-benzoquinoneimine (NAPQI) metabolite (Nelson, 1990) (Figure 8.3)
Do not ever seek or attempt to filter or reuse doubtful solutions
NAC supplies N-acetyl-L-cysteine, which is more stable and better absorbed than its derivative, L-cysteine
5 Pyroptosis 5.1 Pyroptotic signaling pathway Pyroptosis features plasma membrane breakdown along with the release of pro-inflammatory cytokines (159)
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