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KLOW's mechanism as a Klotho mimetic suggests theoretical risks including phosphate dysregulation, hypoglycemia when combined with other glucose-lowering agents, and potential immunogenicity with repeated subcutaneous dosing
On top of that, one of the biggest complaints about GLP-1s, when taken according to the standard doses approved by the FDA is that they cause side effects such as nausea, diarrhea and fatigue
Moreover, GLP-1RAs have neuroprotective, anti-infectious, cardiovascular protective, and metabolic regulatory effects, exhibiting good application prospects
This internal production relies on a steady supply of sulfur-rich foods and specific amino acids
T., Li, J., et al
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