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Subsequently, each system underwent independent simulations lasting 500 ns each (totaling 1.5 s per system) at 298 K, employing the Langevin thermostat with a time step of 0.2 fs
Recent evidence demonstrates that targeting the lactate-ferroptosis axis can reprogram the immunosuppressive tumor microenvironment
J Transl Med 23 , 648 (2025)
New or worsening nephropathy, defined as persistent macroalbuminuria, persistent doubling of the serum creatinine level, and a creatinine clearance of 30 ml/min/1.73 m 2 should receive metformin and SGLT2i (Fig
This includes type 2 diabetes mellitus, obesity, and others
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