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HDAC Inhibition in Rheumatoid Arthritis and Juvenile Idiopathic Arthritis
The rat studies producing the cardiovascular effects described above used 2 to 10 mcg/kg/day, which in a 70 kg adult would correspond to roughly 140 to 700 mcg/day, providing some rough allometric alignment with compounded doses but not a validated human dose
Khr G, Eckardt S, Lddens M, Monyer H, Seeburg PH
Sources: Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH
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