People rarely report any side effects, which are usually mild, such as nausea or temporary discomfort at the injection site
Avoid injecting right before important events or busy workdays, especially during dose escalation weeks when side effects are stronger
Differences were analyzed by one-way or two-way analysis of variance (ANOVA) with Bonferroni post-test, Student t test, multiple t-test with Holm-Sidak method, MannWhitney test, or Mantel-Cox test, as appropriate
The NICE guidance on perioperative care (NG180) emphasises the importance of individualised care and shared decision-making throughout the perioperative period
[...] Even though the carboxylic acid valproate (VPA) is an HDACi with weak inhibitory potential, it is an interesting drug for clinical trials due to its well-characterized pharmacodynamic and pharmacokinetic profile (see Table 6)