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Symptoms of B12 deficiency may include: Depression Fatigue Trouble concentrating Confusion Memory problems Headaches Mood changes Vitamin B12 is essential for red blood cell production, so long-term deficiency can lead to anemia, which can cause fatigue, shortness of breath, and an irregular heartbeat
Some acid-blocking medications, such as PPIs (omeprazole, lansoprazole)which are among the most-prescribed drugs in the U.S
However, very high doses should be avoided unless recommended by a healthcare provider
S.MafongelliE.MannocciA.et al (2014)
About 10% of people with PA test negative on PCA test
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