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Importantly, pharmacological GCL inhibition hindered lymphoma growth in female -MYC mice, suggesting that this treatment holds promise as a therapeutic strategy for female lymphoma/leukemia patients
This notion was confirmed using metabolic cages, revealing that GLP-1MK-801 counteracted the decrease in energy expenditure that is engaged by calorie-restricted mammals as an adaptive starvation response to protect the organism from an excessive loss of body weight and fat mass (Fig
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