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These data also suggest that under conditions favoring fat mobilization and oxidation, hepatic fat is preferentially mobilized over fat from adipose tissue depots

However, the extent of benefit varied substantially

Within the framework of fundamental medicine, the approach proposed by integrative physiology can be the only correct way to view the pathological state of an organism, not from the perspective of the presence of a specific disease or multiple comorbid conditions, but as a complex and unified process based on various links of pathogenesis

They are designed to support appetite regulation and metabolic function through receptor engagement in the gut and brain