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Ample evidence suggests that an imbalance in dopaminergic tone impacts the expression levels of neuropeptides like somatostatin (SST) and neuropeptide Y (NPY), as seen in patients with Parkinsons disease and HD as well as in rodent models 15,16,17,18

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Together they explain why biliary disease is a recognised class effect of GLP-1 therapy

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Target 1.0 to 1.4 grams of protein per pound of lean body mass daily