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In clinical trials of people with type 2 diabetes, Ozempic reduced A1C levels by 1.9%2.2% and caused an average weight loss of 1315 pounds over 10 months

Retrieved March 9, 2020

DPP-4 inhibitors did not lower the risk of any cardiorenal outcome when compared with placebo and were associated with higher risks of MACE, HHF, and renal outcome when compared with the other two drug classes

The FDA does not classify these compounds in traditional pregnancy categories, instead recommending individual risk-benefit assessment by healthcare providers