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doi: 10.2337/db18-0068 89 MallinsonCNBloomSRWarinAPSalmonPRCoxB

Dulaglutide (Trulicity): A once-weekly GLP-1 agonist for type 2 diabetes

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It is worth emphasizing that the gradual approach used did not reduce weight loss or compromise glycemic efficacy, reinforcing that tolerability, not symptom intensity, should guide dose advancement ( A patient centered approach of starting low and going slow prioritizes safety and adherence, building on the principle of doing no harm

The Physical Activity Guidelines for Americans (2023) encourage at least 150 min of moderate-intensity aerobic exercise per week, with a goal of 300 min per week for maximum health benefits