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Blocking the receptors in the arcuate nucleus or in the nodose ganglion does not block the effect, she said, so we really need to focus on these hindbrain NST [nucleus of the solitary tract] neurons. To address the issue of whether GLP-1R agonists applied systemically directly access central GLP-1 receptors, Rinaman showed some images of brain regions with GLP-1 receptors and the axons of GLP-1 neurons labeled in different colors (Farkas et al., 2021)
Comparative effectiveness of GLP-1 receptor agonists on glycemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta-analysis
Novo Shanghai Science and Technology Development Funds 18ZR1447800 (L.H.Z.) and 18431907100 (M.-W.W.)
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13001306, Aug
