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First approved for type 2 diabetes as Ozempic, the higher-dose Wegovy is intended for chronic weight management, delivering semaglutide at 15-20% of the body weight. It acts on GLP-1 receptors in the pancreas, promoting insulin secretion and reducing glucagon, which regulates blood sugar
Lyophilized (freeze-dried) peptides remain stable for years when frozen, whereas pre-mixed liquid formulations rapidly degrade and lose efficacy due to water exposure
It actively increases caloric expenditure, hitting both sides of the energy balance equation at the same time
However, some users swing too far in the opposite direction, eating very little in the evening and then waking hungry during the night
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