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The MHRA-approved Summaries of Product Characteristics (SmPCs) for semaglutide, liraglutide and tirzepatide do not list infertility as a recognised adverse effect, though clinical trials were not specifically designed to detect fertility issues

Shin, M., Bryant, J

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After 5 days without adverse effects, researchers typically increase to 0.5mg daily, then 0.75mg if needed, with 1.0mg daily as the absolute ceiling

As specialists point out, the medications ability to imitate GLP-1 hormone functions is crucial for appetite control, making it a valuable tool for those seeking long-term management of their body composition