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u003cstrongu003eHow often should I microdose semaglutide?u003c/strongu003e You should generally microdose semaglutide once a week because the medication has a long half-life designed for seven-day intervals.u003csupu003eu003ca href=u0022#sources-2u0022u003e[1][18]u003c/au003eu003c/supu003e While splitting the weekly dose into two smaller injections (e.g., every four days) or extending the interval to every 14 days is sometimes suggested in u003ca href=u0022#the-low-and-slow-titration-schedule-2u0022u003emicrodosing protocolsu003c/au003e, this change should only be implemented with guidance from your healthcare provider