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Long-term tolerability and sustainability Some patients may find semaglutide more tolerable over the long term due to its fewer side effects and various long-term health benefits, or due to its simple titration schedule
Weight loss results may vary based on individual factors including starting weight, adherence to medication and lifestyle modifications, and underlying health conditions
A $70 vial that tests at 6.5mg costs $10.77 per actual milligram
At 72 weeks, orforglipron cut body weight by 12.4%, coming slightly ahead of VK2735 (again on a cross-trial basis), but behind the 13.7% weight loss with Novos injectable semaglutide
If nausea becomes a problem, Zofran can be added to help control it
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