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The sleep-improving effects of the CJC-1295/ipamorelin component also help address the cortisol-weight gain cycle driven by menopausal sleep disruption

Gastrointestinal Adverse Events GI AEs are the most frequently reported side effects of GLP-1 RAs and, although typically mild, moderate, and transient, they remain the primary reason for treatment discontinuation among individuals with obesity receiving semaglutide [13, 27, 38, 40,41,42,43,44,45,46, 52]

The high costs of weight loss drugs has been referenced as a major barrier for change