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N Engl J Med 377:12281239 Lee YS, Jun HS (2016) Anti-Inflammatory Effects of GLP-1-based therapies beyond glucose control
However, human clinical safety data remain extremely limited
Brand name versions of both semaglutide and tirzepatide are FDA approved for weight loss in adults with a body mass index (BMI) of 30 or greater (or 27 or greater with at least one weight-related comorbidity)
Rats pretreated with BPC-157 before ethanol administration demonstrated preserved hepatic architecture, lower oxidative stress markers, and maintained glutathione levels compared with untreated controls [6]
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