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This hero works tirelessly to protect your body from damage, toxins, and disease
However, Dox-induced expression of RRM1 and RRM2 alone was not sufficient to revert this protective effect, possibly because of coordinate down-regulation of multiple nucleotide metabolic pathway genes in response to p53 stabilization (Fig 3B)
Some got around this by supplementing with N-acetyl cysteine, which is a precursor to glutathione
Neoplasia 19 , 10221032 (2017)
This "fatty shell" protects the nutrient as it passes through the digestive tract
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