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Materials and methods Study design, participants, and procedures This was a randomized, double-blind, placebo-controlled study with a double-dummy, and crossover design
Understanding who benefits most helps researchers make informed decisions rather than following trends
21,24,25 In some instances, patients may remain on the lowest effective dose and only escalate as needed, such as when weight reduction plateaus
Results In the GLP-1 RA vs SGLT-2 inhibitor cohort (2014-2022) we identified 83,464 new users of GLP-1 RAs and 78,366 new users of SGLT-2 inhibitors
It was also connected to a lower risk of substance abuse
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