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While nutritional VC intake demonstrates chemopreventive effects by scavenging carcinogen-induced reactive oxygen species (ROS) and maintaining genomic stability, high-dose intravenous VC acts as a prooxidant to selectively kill tumor cells via ROS-mediated deoxyribonucleic acid (DNA) damage, adenosine triphosphate (ATP) depletion, and HIF-1 degradation
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
Blood pressure, glycemic markers, lipid profiles, and liver function should be evaluated regularly, alongside changes in body composition and symptom patterns
Proc Natl Acad Sci U S A 118(27):e2026152118
Is glutathione safe during pregnancy and nursing
