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This negative pressure is believed to improve local microcirculation, which helps to increase the delivery of oxygen and nutrients to the affected tissues while removing metabolic waste products (12, 13)

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Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis

[9] TB-500 overexpression lentiviral vector transfected umbilical vein endothelial cells (HUVEC) and murine CLI models