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Retatrutide may become a major future weight loss treatment if approved, but for now it should not be used outside authorised clinical trials

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They were assigned to randomly receive 2.4 mg of semaglutide per week or a placebo, in combination with lifestyle changes

The pathophysiological mechanism of asthma is largely understood as type (T)2-high inflammation, characterized by interleukin (IL)-4, IL-5, and IL-13 and airway eosinophilia, driving airway hyperresponsiveness (AHR) and airway remodeling and leading to airflow obstruction [15]