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Osteoarthritis is a type of arthritis that commonly affects the joints in the hands, hips, and knees
Which certifications are mandatory for GLP-1 weight loss oral solution in North America
Most treatment discontinuations were due to gastrointestinal AE and occurred during the rapid escalation phase this may be mitigated with more gradual dose escalation at phase 3 trials
The Phase 2 obesity trial (Jastreboff et al., NEJM 2023) reported substantial reductions in body weight, with some participants achieving losses exceeding 20% of their baseline body weight at the highest doses studied
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