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Oral is most defensible when the interest is gut lining support, since that is where much of the preclinical research focused and where the oral route delivers directly
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Moreover, the estimated mortality rates of 2.4% and 5.7% for cancers of the lip and oral cavity and the esophagus respectively, and 8.4% along with 11.5% individually for stomach and colorectum cancers, indicated that digestive cancers serve as huge burden for human health (Kumari et al., 2022
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