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Green Tea Extract (EGCG) EGCG (epigallocatechin-3-gallate) supports metabolism and may increase GLP-1 levels
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We hypothesise the inulin will result in greater weight loss maintenance at the 18-week follow-up in subjects with prediabetes, and will promote a reduction in ectopic fat and insulin resistance independent of weight loss assessed by using the gold-standard magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) techniques
Published Phase 2 data provides a timeline for GI adverse event duration: Phase Timeline Stomach Pain Severity Initial dose Weeks 1-2 Onset of GI symptoms mild to moderate cramping and nausea Dose escalation Weeks 2-8 Peak GI discomfort each dose increase can trigger a new wave of symptoms Stabilization Weeks 8-16 Symptoms begin to diminish as the body adapts to stable dosing Maintenance Weeks 16+ Most participants report significant GI symptom improvement or resolution The Phase 2 trial (48 weeks) confirmed that the majority of GI adverse events including stomach pain were concentrated in the dose-escalation period and attenuated over time
Medication makes it easier to adopt healthy habits, while healthy habits improve health outcomes
