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It is imperative to acknowledge that, with the progressive exploration of lactylation, therapeutic strategies targeting lactylation may evolve from elucidating molecular mechanisms to achieving clinical application, ultimately transitioning from bench to bed
Histidine (His): Contains an imidazole ring, key in biochemical reactions
Its compact tetrapeptide structure allows rapid cellular uptake in laboratory models
the decisive Laws 2012 meta-analysis showing essentially no effect in healthy adults
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