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Glutathione is a tripeptide molecule composed of three amino acids: L-glutamine, L-cysteine, and L-glycine
however, most patients eventually develop chemoresistance, leading to treatment failure (9092)
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Further alterations in intracellular redox balance driven by lower GSH availability induce cell death and enhance T2 signature protein expression We previously demonstrated that 15LO1-PEBP1 complex activation consistently upregulates the expression of T2-signature gene/protein expression, including MUC5AC, periostin (POSTN), and CCL26 (6, 10, 14)