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2011)were the first to demonstrate region-specific alterations in the oxidative damage marker 3-nitrotyrosine (3-NT) in postmortem brains of individuals with autism, showing that regions such as the orbitofrontal cortex, Wernickes area, the cerebellar vermis, and the cerebellar hemispheres exhibited distinct levels of this biomarker, reflecting region-specific redox signatures

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453 Indeed, GLP-1RAs, including exenatide, liraglutide, and semaglutide, have been linked to the diminished expression of matrix metalloproteinases (MMPs)

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Another study examined the effects of Liraglutide in obesity mice models, and it has demonstrated anti-inflammatory properties, treatment with Liraglutide has reduced markers of inflammation TNF-, nuclear translocation of nuclear factor kappa B (NFB), prevented adhesion of human monocytes to tumor necrosis factor--activated human endothelial cells in vitro