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Remaining at 8mg long-term is a legitimate outcome, not a failure
Furthermore, the buildup of ototoxic drugs within hair cell mitochondria can result in drug-induced hearing loss (Tan and Song 2023)
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Phase 2 data published in the New England Journal of Medicine (Jastreboff et al., 2023) showed average weight reductions of up to approximately 24% over 48 weeks at the highest doses studied, primarily in adults without type 2 diabetes
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