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The interplay of NAD + /NADP + metabolism with circadian clock is further evidenced by the oscillating redox, in which ROS levels display a different liver pattern compared to other tissues due to the unique NAD + oscillation in response to the autonomous hepatic clock
In 2006, Wood et al
After treating HaCaT with 580 M CuCl 2 or Cu(OAc) 2 , the expression of IL1A, IL8, HSPA1A and FOSL1 were significantly higher than that in the control group and ranged from a 844 fold change
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