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At the cellular level, increased -synuclein deposition correlates with cellular aging, evidenced by elevated numbers of senescent cells and increased -galactosidase expression in postmortem PD brain tissues (54)
Due to the presence of a Cm domain (Supplementary Fig
Another strategy involves the use of PARP inhibitor BGP-15, which might protect against CC, to enhance mitochondrial homeostasis 260,261
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