is semaglutide the same as tripeptide CagriSema vs Tirzepatide vs Retatrutide: Comparing Next-Generation Metabolic Peptides Tirzepatide vs Semaglutide: Weight Loss,

Crit Care Med 27(9):18071813

Those treated with tirzepatide had an average weight loss of 15% to 20% of their starting body weight over 72 weeks (about 16.5 months)

The mean reduction in body weight at 48 weeks was 24.2% in the 12-mg group the largest reduction observed to date in a Phase 2 trial of an anti-obesity medication. Jastreboff et al., New England Journal of Medicine, 2023 Beyond weight loss, retatrutide produced a result that surprised researchers: dramatic reductions in liver fat

The result is that dehydration amplifies medication side effects and makes them difficult to distinguish from pharmacological causes

Myth 4: GLP-1 Medications Work Like Bariatric Surgery GLP-1 medications and bariatric surgery operate in entirely different ways