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Expression of Mcl-1 is upregulated in many cancers, and it was seen to be upregulated as a resistance factor to chemotherapies, Keating says

Plant Cell Physiol 61:15761589 Li Q, Xiang C, Xu L, Cui J, Fu S, Chen B, Yang S, Wang P, Xie Y, Wei M, Wang Z (2020) SMRT sequencing of a full-length transcriptome reveals transcript variants involved in C18 unsaturated fatty acid biosynthesis and metabolism pathways at chilling temperature in Pennisetum giganteum

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Adjusting the dosage under medical supervision is recommended