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In conclusion, these data demonstrated that folate suppresses PBX3 expression in tumor cells, thereby reducing its binding to the CCL5 promoter, decreasing CCL5 secretion and inhibiting CD8 + T cell recruitment

These potential benefits include preserved eGFR, reversal of bone-mineral disorder, decreased risk of progression to dialysis, reduced urinary protein loss, decreased blood phosphate, and reduced all-cause mortality

May provide targeted repair and inflammation support

Nat Struct Mol Biol 30(11):18061815 Hendricks JM et al (2023) Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis