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doi: 10.3389/fpls.2024.1373801 Received 20 January 2024 Accepted 23 February 2024 Published 12 March 2024 Volume 15 - 2024 Edited by Ahmed Abdelkhalek, City of Scientific Research and Technological Applications, Egypt Reviewed by Nuria Montes, Hospital Universitario de La Princesa, Spain Updates Copyright 2024 Kozie, Otulak-Kozie and Rusin

doi: 10.1007/s10067-014-2517-2 PMCID: PMC3962576 The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain Jarred Younger, Luke Parkitny, and David McLain Curr Rheumatol Rev

Notably, it is able to cross the blood-brain barrier, which has made it a subject of ongoing neuroendocrine research

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