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they are consistently most effective when integrated with a programme of supported behaviour change

Muscle Loss If appetite suppression is too high, protein and nutrient intake decreases, leading to: Muscle loss Increased fatigue Reduced metabolic rate Slower recovery after surgery Strength training and sufficient protein (1.2g per kg of body weight) are essential

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Clinicians should not use digoxin in ventricular pre-excitation syndromes such as Wolff-Parkinson-White (WPW), as it may shorten the refractory period of the accessory pathway, trigger rapid ventricular conduction, and cause hemodynamic collapse or sudden cardiac death (56)(58)

The goal in using puberty blockers is thought to allow a person time to further determine their true gender identity before the emergence of permanent sex characteristics