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Potential Side Effects While Vitamin B12 injections are generally safe, some people may experience mild side effects, including: Pain or redness at the injection site Mild diarrhea Itching or rash Headache Dizziness Severe allergic reactions are rare but require immediate medical attention

It depends on what you need

[3] The water itself simply serves as a solvent or vehicle for the drug and does not alter the drugs mechanism of action

Only increase if lower doses plateau and you tolerate well

In addition, oral supplementation is associated with significant cost savings, no side effects and increased compliance, compared to intramuscular injections