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Presented for research literature review only Okita JR et al

Acne is multifactorial, with hormonal influences, stress, dietary factors, and skincare products all potentially contributing

Major risk factors for melasma include sun exposure, hormonal changes, genetics, and having a darker skin type

Modifier 33: Commercial Preventive Screening Signal Append modifier 33 to CPT 45378 (no intervention) or any therapeutic CPT (45380, 45385) on commercial insurance claims when the colonoscopy was ordered as an ACA preventive screening

As with any form of aesthetic treatment, there are some risks associated with acne treatment including dryness and irritation of the skin, increased sensitivity to sunlight, and changes in skin pigmentation