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33 NiW.WangP.ChenH.LiuY.ZhangW.QiuL.et al (2021)

Dong Y, Wang L, Wang J, Wang S, Wang Y, Jin D, et al

the hyperphosphorylation of tau proteins leads to the disruption of microtubule structure and affects mitochondrial axonal transport, exacerbating the neuronal energy crisis (Meng et al., 2024)

Its not one big effect

Figure 1 Potential for differentiation with small molecules Detailed investigation of the small molecule GLP-1 receptor agonist danuglipron showed that, compared to natural GLP-1, the synthetic agonist showed differences in GPCR coupling to the cAMP and B-arrestin downstream biological pathways