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Semaglutide prescriptions, including Ozempic, have also been linked to other health issues, including: Thyroid tumors Diabetic retinopathy Acute kidney injury Increased heart rate Hyperglycemia (high blood sugar) Agitation, irritability, and other abnormal behaviors Stomach paralysis and other gastrointestinal conditions Gallstones The gallbladder stores bile produced by the liver, which aids in digestion
The evidence consistently identifies several factors that increase risk further: Higher doses (the weight-loss doses of semaglutide and tirzepatide carry higher risk than the lower diabetic doses) Longer duration of treatment Faster rate of weight loss Pre-existing gallstones even asymptomatic ones found on a previous scan Female sex, age over 40, and family history of gallstones (the standard baseline risk factors, amplified by GLP-1 therapy) If several of these apply to you, the risk-benefit balance of your treatment plan is worth a structured discussion
Semaglutide kicks it open
Untreated orthostatic hypotension (pressure drops significantly when standing) is a contraindication unless your provider can modify underlying causes first
Are GLP-1R agonists the long-sought-after panacea for obesity
