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Does diet-induced weight loss lead to bone loss in overweight or Obese adults
Those who make it past week 12 have an 89% completion rate through week 48
Fisman EZ, Tenenbaum A
In 2013, Wilson-Perz et al reported another Glp-1r / mouse that was also generated by Cre-LoxP-mediated gene deletion on the C57BL/6 background, and showed that on a high-fat diet, loss of the Glp-1r impairs glucose clearance and insulin secretion in response to a mixed meal challenge
The matched cohorts included 10,339 tirzepatide-treated and 10,339 semaglutide-treated patients
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