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Last lithium level: 1.0 mEq/L six months prior
Variants in FTO (the fat-mass and obesity-associated gene), GLP1R (the GLP-1 receptor gene, the direct target of every GLP-1 compound), MC4R (a melanocortin receptor central to satiety and energy balance), and TCF7L2 (a transcription factor tied to glucose homeostasis and GLP-1 secretion) map the baseline metabolic terrain any compound acts on
Recently, we highlighted two small molecule leaders in the GLP-1R agonism space, orforglipron and danuglipron
However, their potential therapeutic effects extend beyond the endocrine system, suggesting a promising role in the treatment of psychiatric disorders
The use of peptides in chronic disease treatment is a rapidly expanding area of research, with numerous clinical trials underway to explore their full potential
