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If you mean: most established and widely used the answer is semaglutide
The quantitative analysis comprised 24 studies involving a total of 1,032 patients who presented numerical data on changes in selected anthropometric and body composition parameters resulting from GLP-1 RA therapy
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A pesar de la baja incidencia de estos eventos adversos y de la probabilidad de que los beneficios superen estos riesgos en los individuos con obesidad grave, los mdicos y los pacientes deben ser conscientes de estos efectos secundarios graves
These findings should therefore be interpreted as exploratory and hypothesis-generating rather than confirmatory evidence of a direct reproductive effect independent of weight reduction (102)
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