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Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke
Animals were not used for multiple experiments as two of the three experiments were non-survival (due to the blood collection following DMRS and the urethane anesthesia used for fMRI) and incompatible (DMRS and PET both required labeled glucose injection, the DMRS and fMRI signals may interfere with each other, and fMRI required different anesthesia than the other two experiments)
They also have protective effects on the liver in cases of alcohol-related liver disease, MASLD, and NASH, with a relative risk of 2.48 for resolving NASH
Table 2 Testing of melanocortin drugs using in vivo models driven by fibroblasts
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