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However, Lipo C lacks robust clinical trial evidence demonstrating independent weight loss benefits in humans

Gastrointestinal conditions Some gastrointestinal conditions may affect how vitamin B12 is digested or absorbed, such as: history of gastrointestinal surgery celiac disease Crohns disease pernicious anemia infections, such as from Helicobacter pylori bacteria or parasites pancreatic insufficiency or cancer bowel cancer folic acid deficiency small intestinal bacterial overgrowth Vitamin B12 injections may be more helpful for people with gastrointestinal conditions than oral products

Appetite changes come first

GLP-1 is a class of weight-loss and diabetes injections semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro)

Eating well on both medications The Wegovy pill reduces appetite and quietens food noise, but the aim isnt to eat as little as possible, as this can impact thyroid function and increase the risk of muscle loss and nutrient deficiencies