Gopal Grandhige, MD, FACS, Board-Certified Surgeon Last Reviewed: April 29, 2026 Not eating enough protein on tirzepatide can lead to accelerated muscle loss, a slower metabolism, chronic fatigue, hair thinning, weakened immunity, and weight loss results that dont last
If you're struggling with weight management despite your best efforts with diet and exercise, tirzepatide could be the solution
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You may lose 2-4 pounds per week during the initial weeks at this dose
Semaglutide is a medication that mimics the effect of GLP-1, a hormone produced in your gut after you eat, and it has several effects on your body, such as: Stimulating insulin secretion and lowering blood sugar levels Slowing down gastric emptying and reducing food intake Increasing energy expenditure and fat-burning Reducing appetite and hunger Enhancing satiety and fullness Semaglutide was originally approved by the FDA as a treatment for type 2 diabetes, and in 2021, it was approved for chronic weight management in adults