In murine experiments, exposure to PS-MPs resulted in neurobehavioral changes characterized by increased latency in reaching a platform and impaired spatial learning and cognitive function, as evidenced by the water maze test
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Stability of GSH under large input fluctuations Hepatocytes are seldom at steady state [21] because they receive large protein inputs during and shortly after meals and relatively little protein input between meals
Results FoB and MZB exhibit distinct glutathione-based redox dependencies To dissect the redox state of MZB and FoB in relation to the main antioxidant GSH, we studied the expression of Gclc , which is necessary for GSH synthesis 24 , in isolated MZB and FoB from spleens of C57BL/6J (B6 or wild-type) mice