Co-primary end point measuring mean change in body weight (%) from baseline Please see full study designs by clicking the link above
Currently, seven AOMs are approved by both the Food and Drug Administration (FDA) and European Medicines Agency (EMA) -liraglutide, semaglutide, tirzepatide, orlistat, naltrexone/bupropion, setmelanotide, and metreleptin- while two additional agents (phentermine and phentermine/topiramate) are FDA-approved only
Tepwong P, Giri A, Sasaki F, Fukui R, Ohshima T
Because Mounjaro is not FDA-approved for weight loss, however, commercial insurance plans (such as BCBS) may or may not cover this medicine for this purpose (but will often cover it for diabetes)
Avoid Extreme Temperatures: The medication should be kept out of sunbeams, high temperatures or cold